BBC.com reports that teeth can be encouraged to self-repair. This is according to a report from scientists at King’s College London. It appears that there’s a chemical that can support cells in the dental pulp to heal small holes in mice teeth.
They made use of a biodegradable sponge. It was then soaked in the drug and then put inside the cavity. The study was released in Science Reports. “It led to a complete and effective natural repair.
Teeth only have little regenerative abilities. They release a thin band of dentine, the layer just below the enamel. If the inner dental pulp gets exposed, it does not have the capacity to repair a large cavity. To repair tooth decay, dentists need to make use of a filling made of metal amalgam or a composite of powdered glass and ceramic.
But in this case, this could be a brand new way for dental repair:
Tooth Repair Drug’ May Replace Fillings
They discovered that a drug called Tideglusib heightened the activity of stem cells in the dental pulp so they could repair 0.13mm holes in the teeth of mice. A drug-soaked sponge was placed in the hole and then a protective coating was applied over the top. As the sponge broke down it was replaced by dentine, healing the tooth. Read more…
The drug, Tideglusib, was originally developed to manage Alzheimer’s disease. However, as the research shows, it is quite effective when it comes to treating tooth decay. Medical Daily discusses that the drug is approved for use in Alzheimer’s cases, hence, there will be less need to test its safety.
The study was released in Scientific Reports. Tideglusib facilitated dentine production in the tooth. Because the process is so simple, it is very ideal as a dental product. As it exhibits pulp protection and dentine restoration, it may be produced for the treatment of large cavities. This is according to study author Paul Sharpe.
Moreover, what’s really good is that in cases of tooth decay, the approach speeds up the generation of stem cells and the damage will not progress. This also means it would eliminate the need for fillings.
Tooth Decay Eliminated With Alzheimer’s Drug? Treatment Speeds Up Tooth Repair, May Replace Fillings
Every so often we come across a drug developed to treat one condition that unexpectedly does wonders for an unrelated problem; a new and prime example is the drug Tideglusib. Although originally developed to treat Alzheimer’s disease, new research suggests that it could actually do wonders for tooth decay, perhaps making the dreaded root canal a barbaric procedure of the past. Read more…
The Telegraph UK explains that fillings could no longer be needed because of the main function of this drug. Scientists were able to show that aside from triggering the production of dentine, it also repairs the damage in just six weeks. The little sponges are also convenient because they’re made out of collagen: these melt away over time.
Dr Nigel Carter, CEO of the Oral Health Foundation says that this approach promises a good outcome for dental health. For the process to be initiated into clinical application would mean that it is a progressive step towards the treatment of dental issues.
This is a more natural way of solving dental problems. It presents a less invasive option for patients. While dental phobia is as real as it gets, this technique can prove to be comforting for the public.
End Of Fillings In Sight As Scientists Find Alzheimer’s Drug Makes Teeth Grow Back
Researchers at King’s College London found that the drug Tideglusib stimulates the stem cells contained in the pulp of teeth so that they generate new dentine – the mineralised material under the enamel. Read more…
Though this discovery gives us hope about a better form of treatment, don’t cancel your appointments to the dentist just yet. It remains to be seen whether this is going to be available for the public. Further investigations are needed. In the meantime, prioritize proper mouth hygiene, tooth care, and regular visits to your dentist.